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Research—Disease—AHPND/EMS, For Geneticists Only

 

Shrimp News: This study is loaded with complex genetic terminology and technical scientific expressions.  If you don’t understand the abstract (below), you’re probably not going to understand the full study.  I did not understand any of it, but thought it might be important!

 

From Abstract (A full copy of the study is available at this link): Acute hepatopancreatic necrosis disease (AHPND) is a severe shrimp disease originally shown to be caused by virulent strains of Vibrio parahaemolyticus (VPAHPND).  Rare cases of AHPND caused by Vibrio species other than V. parahaemolyticus have been reported.  Here we compare an AHPND-causing V. campbellii (VCAHPND) and a VPAHPND isolate from the same AHPND-affected pond.  Both strains are positive for the virulence gene pirABvp.  Immersion challenge test with Litopenaeus vannamei indicated the two strains possessed similar pathogenicity.  Complete genome comparison showed that the pirABvp-bearing plasmids in the two strains were highly homologous, and they both shared high homologies with plasmid pVA1, the reported pirABvp-bearing plasmid.  Conjugation and DNA-uptake genes were found on the pVA1-type plasmids and the host chromosomes, respectively, which may facilitate the dissemination of pirABvp.  Novel variations likely driven by ISVal1 in the genetic contexts of the pirABvp genes were found in the two strains.  Moreover, the VCAHPND isolate additionally contains multiple antibiotic resistance genes, which may bring difficulties to control its future outbreak.  The dissemination of the pirABvp in non-parahaemolyticus Vibrio also rises the concern of missing detection in industrial settings since the isolation method currently used mainly targeting V. parahaemolyticus.  This study provides timely information for better understanding of the causes of AHPND and molecular epidemiology of pirABvp and also appeals for precautions on the dissemination of the hazardous genes.

 

Source: Frontiers in Microbiology/Infectious Diseases.  pirABvp-Bearing Vibrio parahaemolyticus and Vibrio campbellii Pathogens Isolated from the Same AHPND-Affected Pond Possess Highly Similar Pathogenic Plasmids.  Xuan Dong, Dexi Bi, Hailiang Wang, Peizhuo Zou, Guosi Xie, Xiaoyuan Wan, Qian Yang, Yanping Zhu, Mengmeng Chen, Chengcheng Guo, Zhen Liu, Wenchao Wang and Jie Huang*.  October 5, 2017.

 

*Corresponding Author: Jie Huang, Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture, Qingdao Key Laboratory of Mariculture Epidemiology and Biosecurity, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, China (Email huangjie@ysfri.ac.cn, Phone +86-0532-85823062, Fax +86-0532-85811514).

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